How long does it take Nexium to start working?

Results can vary, but individuals who take Nexium for acid reflux disease often experience reduced symptoms within 24 hours of taking the medication, according to Nexium. When the medication is used to treat acid erosion of the esophagus, symptoms are typically relieved within four to eight weeks.

Individuals who are taking Nexium should stop taking the medicine and consult with a physician if they experience side effects such as dizziness, rapid heart rate, coughing or diarrhea, according to Drugs.com. People should seek immediate medical attention if they experience symptoms of hives, swelling or breathing difficulties after taking Nexium, as these symptoms can indicate a severe allergic reaction.