What are the side effects to acetaminophen and codeine?

Common side effects of acetaminophen and codeine include nausea and vomiting, constipation and mild stomach upset according to Drugs.com. Drowsiness, dizziness and light-headedness are additional side effects of this medication.

Serious side effects of acetaminophen and codeine include systemic allergic reaction, confusion, fainting, difficulty urinating and mental or mood changes, notes Drugs.com. Fever and chills, unusual fatigue and weakness and symptoms of liver disease are additional side effects requiring immediate medical care.

Those who have a history of liver, kidney, thyroid or adrenal disease should use acetaminophen and codeine with care, suggests PDR Health. Those with stomach problems, such as ulcers, and those with head injuries, an enlarged prostate or difficulty with urination should also use this medication carefully.