What are the side effects of the zoster vaccine?

The most common side effects of the zoster vaccine, which protects the recipient against shingles, are pain, warmth, redness, itching, swelling and bruising at the site of the injection, according to eMedicineHealth. Headache, diarrhea, joint or muscle pain and a mild skin rash may develop as well.

Serious side effects of the zoster vaccine that require medical attention include flu-like symptoms, such as sore throat, fever and swollen glands, breathing issues and a severe or painful skin rash, advises eMedicineHealth. If hives or breathing difficulties develop or swelling of the face, lips, tongue or throat occurs, emergency medical attention is necessary.