Which statin drugs have the fewest side effects?

Zocor and Pravachol cause the fewest side effects of all the statin drugs, according to WebMD. Statin drugs, as a class, produce very few side effects.

Studies have shown that statins produce more benefits than harm, even when they cause side effects. Statin drugs lower low-density lipoprotein, or LDL, also known as bad cholesterol in the blood by reducing cholesterol production in the liver. They also stabilize plaque on artery walls. There are numerous statin drugs available, including Lipitor, which is one of the most popular. Most of these drugs produce mild side effects like nausea, headache, diarrhea, weakness, skin rashes and muscle pains, according to MedicineNet.