What is the cause of a tingling sensation in the lower right leg?

A tingling sensation in the lower right leg can be caused by numerous health problems including nerve damage, vitamin deficiencies or standing and sitting for a prolonged period, according to MedlinePlus. Other causes of a tingling sensation in one or both legs are animal bites, seafood toxins, lack of proper blood flow to the affected area and radiation therapy.

Tingling sensations can occur anywhere throughout the body, but the most common areas where tingling can occur are legs, arms, feet and hands. Since there are a wide range of reasons why someone might be experiencing a tingling sensation in their extremities, it is important to consult with a doctor for a proper diagnosis and treatment plan.