Is an NO2 supplement safe?

According to eSupplements.com, NO2 is safe if taken as recommended and if a healthy diet and regular exercise are maintained. Consult a doctor if taking medications to guard against drug interaction. This is especially important if you have high blood pressure or diabetes.

NO2 has side effects. Although this side effect is rare, NO2 reduces dopamine levels in the brain which may have a negative effect on motivation levels, sleep cycles, cognitive skills as well as long and short term memory. Histidine is an acid often found in supplements that may deplete zinc levels in the body. High levels of histidine may cause diarrhea, impotence, impaired appetite and delayed sexual maturation. This side effect can be avoided by adding foods rich in zinc, such as crabs, oysters, peanuts and pumpkin seeds, to one's diet. Stomach cramps and nausea is another side effect. This side effect can be managed by starting with small doses and slowly increasing the dosage until the recommended dosage is reached.