What is the proper dosage for nattokinase?

As of December 2015, there is no sufficient scientific information to determine the proper dose for nattokinase, explains WebMD. The dosage depends on factors such as health and age, among other conditions. Some studies have used between 100 to 300 milligrams daily, states Drugs.com.

Nattokinase is an enzyme that works by speeding up biochemical reactions in the body, explains WebMD. It is extracted from natto, a Japanese food used as remedy for cardiovascular diseases. As it acts as a clot thinner, it might make bleeding disorders worse. Patients should stop taking nattokinase at least two weeks before going for surgery.