When is the best time to take creatine?

Researchers say that taking creatine along with a carbohydrate or protein supplement after a workout is most effective, according to Men's Health. Taking creatine with a carbohydrate or protein supplement helps to increase a body's insulin production and assist with creatine uptake.

Men's Fitness indicates that creatine helps to boost muscle mass and strength, and men who took creatine after they worked out saw more lean muscle mass gain compared to those who took creatine before they worked out. Those men also saw an increase in their bench-press one-rep maximum. Aside from building muscle size, creatine helps boost testosterone productivity.