What is the treatment for E. coli?

The primary treatment for illness from E. coli is rest and fluids. The Mayo Clinic states that most illnesses caused by E. coli are self-limiting and do not require treatment. However, serious E. coli infections can cause hemolytic uremic syndrome, which does require supportive care in a hospital.

The majority of people who contract E. coli need only rest and fluids for their treatment. Avoid taking antidiarrheal medication so that the bacteria is able to leave the body; taking antidiarrheal medication slows down a patient's digestive system and prolongs the time the bacteria is in his body. Antibiotics are not used to treat illnesses related to E. coli because the drugs potentially cause a variety of complications, according to the Mayo Clinic.