How many calories are there in a slice of pizza?

On average, there are 168 calories in a single slice of plain cheese pizza, with 54 of these calories coming from fat. The number of calories in one slice of pizza increases if toppings are added.

Pizza toppings add to the caloric content of a slice of pizza. For example, a slice of pepperoni pizza contains 181 calories, while a slice of Pizza Hut pan pizza supreme contains 290 calories. The calories in a slice of pizza also vary by the brand or vendor of the pizza. Domino's meat lover's pizza contains 217 calories, while Lean Cuisine's three meat pizza contains 370 calories.